The short answer
Review supply risk early and track important components during the programme. If an end-of-life notice arrives, the options may include a final purchase, an alternative part or a design update.
In more detail
The component list should identify parts that are difficult to replace, including displays, processors and specialist sensors. Availability information needs to come from the relevant supplier.
A replacement can affect software, power, radio performance or certification. It needs validation before use, even if the package or pin layout looks similar.